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Perinatal death triples the prevalence of postpartum depression among women in Northern Uganda:
(PLOS ONE, 2020-10-10) OjokArach , Anna Agnes .; Nakasujja ,Noeline; Nankabirwa, Victoria; Ndeezi , Grace; Kigule, Juliet .; Mukunya , David; JustinOdongkara , Beatrice; Tylleskar , Thorkild; Achora , Vincentina; Tongun , Bruno Justin; Wamboko Musaba , Milton; Tumwine , JamesK.; Napyo, Agnes; Zalwango , Vivian; Tylleskar , Thorkild; Tumwine ,K. James
Abstract
Introduction
Deaths during the perinatal period remain a big challenge in Africa, with 38 deaths per 1000 pregnancies in Uganda. The consequences of these deaths can be detrimental to the women; some ending up with postpartum depression. We examined the association between perinatal death and postpartum depression among women in Lira district, Northern Uganda.
Methods
We conducted a community-based cross-sectional study of 1,789 women. Trained research assistants screened women for postpartum depressive symptoms on day 50 postpartum using the Edinburgh postpartum depression scale (EPDS). Socio-demographic, economic, birth and survival status of the neonate were collected during pregnancy and within one week postpartum. We used generalized estimating equation for the Poisson family with a log link using Stata to estimate the prevalence ratio of the association between postpartum depressive symptoms (EPDS scores ≥14) and perinatal death. Mothers who lost their babies between 7–49 days postpartum were excluded.
Results
Of the 1,789 participants symptomatically screened for postpartum depression, 377 (21.1%) [95% confidence interval (95%CI): 17.2%, 23.0%] had probable depressive symptoms. The prevalence of postpartum depressive symptoms among the 77 women who had experienced perinatal death (37 stillbirths and 40 early neonatal deaths (≤7 days of life)) was 62.3% [95% CI: 50.8%, 72.6%] compared to 19.2% [95% CI: 17.4%, 21.2%], among 1,712 with live infants at day 50 postpartum. Women who had experienced a perinatal death were three times as likely to have postpartum depressive symptoms as those who had a live birth [adjusted prevalence ratio 3.45 (95% CI: 2.67, 4.48)].
Conclusions
The prevalence of postpartum depressive symptoms, assessed by EPDS, was high among women who had had a perinatal death in Northern Uganda. Women experiencing a perinatal death need to be screened for postpartum depressive symptoms in order to intervene and reduce associated morbidity.
Prevalence and predictors for unintended pregnancy among HIV‑infected pregnant women in Lira, Northern Uganda:
(Nature Research, 2020-10-01) Napyo , Agnes .; Nankabirwa, Victoria.; Mukunya , David .; Tumuhamye, Josephine .; Ndeezi , Grace .; Ojok Arach, Anna Agnes .; Odongkara , Beatrice.; Waako , Paul .; Tylleskär , Thorkild; Tumwine , James K.
Prevention of unintended pregnancies is a global strategy to eliminate mother-to-child transmission of HIV. Factors surrounding unintended pregnancy among women living with HIV are not well understood. We aimed to determine the prevalence and predictors for unintended pregnancy among these women in Northern Uganda. We conducted a cross-sectional survey among 518 women using a structured questionnaire. We asked questions on socio-demographic, reproductive-related and HIV-related characteristics. We conducted multivariable logistic regression and reported adjusted odds ratios. The prevalence of unintended pregnancy was 41.1%. The predictors for unintended pregnancy were: being single (not living with a partner or being in a marital union), having five or more children and taking antiretroviral drugs for long periods of time. HIV counselling services should target women living with HIV who are not in a marital union, those having a higher parity and those who have taken ART for longer periods.
Optimization of pyrolysis conditions for char production from rice husks and its characterization as a precursor for production of activated carbon
(Springer, 2019-03-13) Menya, E.; Olupot, P. W.; Storz, H.; Lubwama, M.; Kiros, Y.; John, M. J.
Response surface methodology was employed to optimize pyrolysis conditions for production of char with maximum yield, fixed carbon content, and with minimum ash content from Uganda’s New Rice for Africa (NERICA) 1 rice husk variety. The aim was to obtain rice husk char with more suitable properties as an activated carbon precursor. Mathematical models were developed to explain the relationships between the experimental responses and the pyrolysis parameters of temperature (400–600 °C), heating rate (10–25 °C min−1), and heating period (60–120 min). The optimized rice husk char was further characterized for elemental and proximate compositions, thermal behavior, specific surface area, as well as surface functional groups. Results from the analysis of variance (ANOVA) revealed that the quadratic model best fits each of the responses. Pyrolysis temperature had the greatest influence on each of the responses, followed by heating period, and lastly heating rate. Optimum pyrolysis conditions were found to be temperature (406 °C), heating rate (10 °C min−1), and heating period (60 min), resulting in char yield, fixed carbon, and ash contents of 35.26, 55.39, and 35.01% dry basis, respectively. Compared to raw rice husk, the resulting rice husk char was found more suited as activated carbon precursor, due to its enriched carbon content (60.35%) and specific surface area (123.9 m2 g−1). Thermogravimetric analysis of the rice husk char revealed that thermal activation temperatures higher than 400 °C may be required to considerably devolatilize the char, forming a more porous activated carbon.
Synthesis and evaluation of activated carbon from rice husks for removal of humic acid from water
(Springer, 2020-11-26) Menya, E.; Olupot, P. W.; Storz, H.; Lubwama, M.; Kiros, Y.
Activated carbon was synthesized from the New Rice for Africa (NERICA) rice husk variety, followed by its evaluation for removal of humic acid from water. Product values of carbon yield, C and total specific surface area, as,BET were employed as the performance criterion. The best physically activated carbon resulted from char activation at 800 °C for 10 min, leading to as,BET and C×as,BET values of 756.8 and 402.7 m2 g−1, respectively. The best chemically activated carbon resulted from 30 wt% H3PO4 activation of rice husk at 400 °C for 30 min, leading to as,BET and C×as,BET values of 2258.4 and 1058.7 m2 g−1, respectively. Despite the higher as,BET value, the maximum adsorption capacity of the best chemically activated carbon (5.3 mg g−1) was found lower than 8.9 and 27.2 mg g−1 exhibited by the chemically activated carbons prepared at 500 and 600 °C, respectively. The best adsorption conditions included carbon dose of 0.5 g, solution pH of 2, and contact time of 60 min. The adsorption capacity of the prepared activated carbons (27.2 mg g−1) was comparable to that of the commercial activated carbon (30.40 mg g−1). The analyses of the adsorption isotherms and kinetics revealed that the experimental data fits well the Langmuir isotherm model, as well as the pseudo-second-order kinetic model. The latter suggests that the adsorption of humic acid onto the activated carbon was controlled by the chemisorption process. Overall, the study revealed that the NERICA rice husk variety has good prospects for preparation of activated carbons for humic acid adsorption.
Progress in deployment of biomass-based activated carbon in point-of-use filters for removal of emerging contaminants from water: A review
(Elsevier, 2023-03-01) Menya, Emmanuel; Jjagwe, Joseph; Kalibbala, Herbert Mpagi; Storz, Henning; Olupot, Peter Wilberforce
Emerging contaminants (ECs) are increasingly being detected in drinking water, posing numerous public health concerns. Granular activated carbon (GAC) offers good prospects for removing ECs at point-of-use (POU), enabling households to have access to safe water. This paper reviews the current advances in deployment of biomass-derived GACs (B-GACs) for removal of ECs at POU. It highlights key sources, pathways and impacts of ECs on public health. It also reveals preparation routes and performance aspects of B-GACs for POU water purification. Knowledge gaps on the subject matter were identified. The review revealed that shells of nuts, which are typically hard and of high density are the most investigated for valorization into GAC for POU water purification. To encourage wide application of B-GACs for POU water purification, there is need to tailor available soft, low-density biomass wastes and suit them as GAC precursors for removal of ECs at the point of use. Future studies need to focus on tailoring the production of B-GACs for removal of specific ECs from water. Additional future research insights include identification of regeneration options for B-GACs, options for removal of residual nanoparticles from the filtrate, lifecycle analysis and costing of various GAC-based POU water filters.