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Item Evaluating the role of perceived usefulness in user adoption of mobile immunisation notification system in Uganda(Inderscience Enterprises Ltd., 2017) Abandu, J. and; Kivunike, F.N.The study sought to evaluate the role of perceived usefulness in user adoption of mobile immunisation-notification system in Uganda. Descriptive survey design was employed and structured questionnaires were administered to 51 healthcare professionals and mothers from Gulu referral and Gulu independent hospitals in Northern Uganda using purposive sampling technique. Regression analysis was performed to evaluate the impact of the identified antecedents on the intention to adopt IMUNOT through perceived usefulness based on technology acceptance model. The findings showed e-health knowledge, accessibility, support, content and trust as the antecedents of perceived usefulness with 87.8% of variance. The findings suggest the importance of perceived usefulness in the mobile Immunisation-notification system adoption. The study provides behavioural and infrastructural strategies for stakeholders on how to foster perceived usefulness in the system adoption. However, more variables may be evaluated to improve the analytical capability of the model.