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Access to the World Health Organization-recommended essential diagnostics for invasive fungal infections in critical care and cancer patients in Africa: A diagnostic survey
(Journal of Infection and Public Health, 2023-08-16)Background: Invasive fungal infections (IFIs) contribute to significant morbidity and mortality among patients with haemato-oncological conditions, seriously ill hospitalised patients and those in intensive care (ICU). We ... -
Improving mycetoma case detection through the training of community health workers in Northern Uganda: protocol for a steppedwedge cluster-randomized trial
(Therapeutic Advances in Infectious Disease, 2023-08-14)Introduction: The World Health Organization acknowledges the need for countries to incorporate neglected tropical disease care into their routine health care system. However, low detection rates and late presentation of ... -
Breakthrough mother-to-child transmission of HIV in a low-health facility in Uganda
(Elsevier Ltd, 2023-07-29)Objectives: Mother-to-child transmission (MTCT) of HIV can be minimized using elimination of MTCT (eMTCT) services. This study aimed to determine the proportion of infants who tested positive for HIV despite receiving eMTCT ... -
Azole-Containing Agar Plates and Antifungal Susceptibility Testing for the Detection of Azole-Resistant Aspergillus Species in Hospital Environmental Samples
(Mary Ann Liebert, 2023)The indoor environment of hospitals should be considered as an important reservoir of azole resistant Aspergillus species. In this study, we evaluated azole-containing agar plates (ACAPs) and antifungal susceptibility ... -
HIV and fungal priority pathogens
(Europe PMC Funders Group, 2023-11-01)The burden of invasive fungal infections associated with opportunistic fungal pathogens is a persistent challenge, particularly among people with advanced HIV disease. In October,2022, WHO published the Fungal Priority ... -
Long COVID in Uganda: Electrographic findings among patients at risk
(Wiley, 2023-03-13)Background: COVID-19 has a significant cardiovascular involvement. An electrocardiographic (ECG) abnormalities among people at a risk of Long COVID in Uganda was investigated. Methods: A cross-sectional study was conducted ... -
Predominance of Trichophyton tonsurans causing tinea capitis: A 12-year retrospective study in the north of Iran
(Current Medical Mycology, 2023-07-13)Background and Purpose: Among different clinical entities of dermatophytosis, tineacapitis (TC) is considered a major public health challenge in the world, especially in regions with poor health and low income. Therefore, ... -
Burden and associated phenotypic characteristics of tuberculosis infection in adult Africans with diabetes: a systematic review
(Springer Nature, 2023)Diabetes mellitus (DM) increases the risk of developing tuberculosis infection (TBI). However, the evidence on the burden and phenotypic characteristics of TBI in African patients with DM is limited. This study aimed to ... -
Partnering to Improve Mentorship Capacity for Ugandan Reproductive Health Researchers: Program Description and Evaluation
(The American Journal of Tropical Medicine and Hygiene, 2023-11-20)Mentorship is essential to health researchers in achieving their full potential and advancing public health. In most low-resource settings, there is a paucity of training on how to be a successful mentor. The Center for ... -
Self-Reported Hypertension and Associated Factors Among Adults in Butambala District, Central Uganda: A Community-Based Prevalence Study
(Integrated Blood Pressure Control, 2023-11-08)Background: The prevalence of hypertension (HTN) differs among regions and income groups, showing a substantial increase in low- and middle-income countries. The development of hypertension is modulated by modifiable ... -
The first Helicobacter pylori-induced Guillain–Barré syndrome in Sudan
(Wiley, 2023-10-31)We report the first known case of Guillain–Barré syndrome (GBS) associated with Helicobacter pylori infection in Sudan. This case highlights the role of H.pylori infection in the development of GBS. It also emphasizes the ... -
"I thought I was going to die": Experiences of COVID-19 patients managed at home in Uganda
(PLOS ONE, 2023-12-12)Background In Uganda, approximately 170,000 confirmed COVID-19 cases and 3,630 deaths have been reported as of January 2023. At the start of the second COVID-19 wave, the Ugandan health system was overwhelmed with a ... -
Isolated renal and urinary tract aspergillosis: a systematic review
(Sage Publications, 2023-11-16)Abstract Background: Aspergillosis localized to the kidneys and the urinary tract is uncommon. We conducted a comprehensive systematic review to evaluate risk factors and clinical outcomes of patients with isolated renal ... -
Prevalence of chronic pulmonary aspergillosis along the continuum of pulmonary tuberculosis care: A protocol for a living systematic review and meta-analysis
(PLOS ONE, 2023-12-15)Introduction Chronic pulmonary aspergillosis (CPA) is a debilitating disease estimated to affect over 3million people worldwide. Pulmonary tuberculosis (PTB) is the most significant risk factor for CPA. However, the true ... -
Diagnostic Accuracy of Clinical Diagnostic Scoring Systems for Childhood Tuberculosis: A Systematic Review and Meta-analysis
(Oxford University Press, 2023-12-11)Background. Diagnosis of childhood tuberculosis (TB) poses several challenges. Therefore, point-based scoring systems and diagnostic algorithms have been developed to improve the diagnostic yields in this population. ... -
Cor pulmonale complicating chronic pulmonary aspergillosis with fatal consequences: Experience from Uganda
(Medical mycology case reports, 2019-07-04)Cor pulmonale is a rare complication of pulmonary aspergillosis (CPA). A 45-year-old Ugandan male with a history of recurrent community-acquired pneumonias was admitted with symptoms of progressive difficulty in breathing, ... -
Innate and Adaptive Immune Defects in Chronic Pulmonary Aspergillosis
(Journal of Fungi, 2017-05-29)We evaluated the expression of biomarkers of innate and adaptive immune response in correlation with underlying conditions in 144 patients with chronic pulmonary aspergillosis (CPA). Patients with complete medical and ... -
Isavuconazole and voriconazole for the treatment of chronic pulmonary aspergillosis: A retrospective comparison of rates of adverse events
(Mycoses, 2018-12-13)Background: Long-term oral triazole antifungal therapy is the cornerstone of man agement for patients with chronic pulmonary aspergillosis (CPA). Itraconazole is the first-line choice of treatment. Voriconazole, posaconazole ... -
Internal Medicine Clerkship Amidst COVID-19 Pandemic: A Cross-Sectional Study of the Clinical Learning Experience of Undergraduate Medical Students at Makerere University, Uganda
(Dove Press, 2021)Background: The coronavirus-2019 (COVID-19) pandemic continues to impose a significant impact on medical education. We aimed to describe the clinical learning experience of undergraduate medical students undertaking ... -
COVID-19 vaccine acceptance among high-risk populations in Uganda
(Therapeutic Advances in Infectious Disease, 2021)Background: Immunization is an important strategy for controlling the COVID-19 pandemic. COVID-19 vaccination was recently launched in Uganda, with prioritization to healthcare workers and high-risk individuals. In ...