Long COVID in Uganda: Electrographic findings among patients at risk

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dc.contributor.authorSemulimi, Andrew Weil
dc.contributor.authorBatte, Charles
dc.contributor.authorIraguha, Daniel
dc.contributor.authorOkwir, Pamela Apio
dc.contributor.authorAtuhaire, Hope
dc.contributor.authorLipoto, Chelsea
dc.contributor.authorMuwonge, Tonny
dc.contributor.authorNamirembe, Norah
dc.contributor.authorLubega, Grace Biyinzika
dc.contributor.authorAinembabazi, Provia
dc.contributor.authorMukisa, John
dc.contributor.authorBongomin, Felix
dc.contributor.authorSsinabulya, Isaac
dc.contributor.authorOkello, Emmy
dc.date.accessioned2024-02-05T12:33:43Z
dc.date.available2024-02-05T12:33:43Z
dc.date.issued2023-03-13
dc.description.abstractBackground: COVID-19 has a significant cardiovascular involvement. An electrocardiographic (ECG) abnormalities among people at a risk of Long COVID in Uganda was investigated. Methods: A cross-sectional study was conducted from February to June 2022 at the post COVID-19 clinic in Mulago National Specialized Hospital, Kampala. A standard resting ECG was performed on individuals at least 2 months following acute COVID-19, with a negative SARS-CoV-2 reverse-transcription polymerase chain reaction. Socio-demographic and clinical characteristics as well as vital signs were recorded for all study participants. Results: Of the 244 study participants, 117 (47.9%) were female. The median age of all the participants was 33.0 (interquartile range: 26.0–43.5) years. Twenty-five (10.2%) participants had a history of smoking, whereas 117 (48%) had a history of alcohol intake. In total, 46 (18.9%) had abnormal ECG findings (95% Confidence Interval [CI]: 14.39–24.29), and nonspecific T-wave inversion (n = 16, 34%) was the most frequent ECG abnormality. The proportion of participants with ECG abnormalities was 48% lower among females (adjusted prevalence ratio [aPR]: 0.52, 95% CI: 0.28–0.96, p value <0.05) and twofold greater for those with a history of smoking (aPR: 2.03, 95% CI: 1.096–3.776, p value <0.05). Conclusion: One in five Ugandans who were checked at the clinic at a risk of Long COVID showed ECG abnormalities. ECG screening is suggested to be integrated into the follow-up care of those at a risk of Long COVIDen_US
dc.description.sponsorshipThe study was supported by National Institute of Health Research through the Royal Society of Medicine and Hygiene (RSTMH) 2021 Early Career grants. Additional funding for the study is from the Makerere University Non-Communicable Diseases (MAKNCD) Research Training Program with support from the Fogarty International Center of the National Institutes of Health under Award Number D43TW011401.en_US
dc.identifier.uri: 10.1002/puh2.78
dc.identifier.urihttps://hdl.handle.net/20.500.14270/457
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofseriesPublic Health Chall.;2023;2
dc.subjectAfricaen_US
dc.subjectcardiac arrhythmiasen_US
dc.subjectcardiac conduction system diseaseen_US
dc.subjectLong COVIDen_US
dc.subjectmyocardial ischemiaen_US
dc.subjectpandemicen_US
dc.subjectpost-acute COVID-19 syndromeen_US
dc.titleLong COVID in Uganda: Electrographic findings among patients at risken_US
dc.typeArticleen_US

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