Clinical Characteristics and Outcomes of Patients Hospitalized with COVID-19 at Case Hospital, Uganda
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Date
2022-06-08
Authors
Apiyo, Mirriam
Olum, Ronald
Kabuye, Amina
Khainza, Betty
Amate, Anne M.
Byabashaija, Vittal
Nomujuni, Derrick
Sebbaale, Kato
Senfuka, Peter
Kazibwe, Simon
Journal Title
Journal ISSN
Volume Title
Publisher
Interdisciplinary Perspectives on Infectious Diseases
Abstract
Data on clinical outcomes of patients hospitalized with coronavirus disease 2019 (COVID-19) in private health facilities in Uganda
is scarce. We conducted a retrospective cohort study of patients hospitalized with COVID-19 at Case Hospital, Kampala, Uganda,
between June 2020 and September 2021. Data of 160 participants (median age 45 years (interquartile range [IQR]: 37–57) and
63.5% male) was analyzed. Seventy-seven (48.1%) participants had non-severe, 18 (11.3%) severe, and 83 (51.9%) critical COVID 19 illness. In 62 participants with chest computed tomography £ndings, 54 (87%) had bilateral disease, with 22 (35%) having
ground-glass opacities. e median duration of hospitalization was 5 days (IQR: 3–9 days). Overall, 18 (11.3%) participants died.
Survival at 14 and 28 days was 89% and 72%, respectively. Factors strongly associated with all-cause mortality were as follows: age
>50 years (odds ratio [OR]: 8.6, 95% con£dence interval [CI]: 1.1–69.2, and p 0.042), having at least 1 comorbidity (OR: 3.2, 95%
CI: 1.1–8.9, and p 0.029), hypertension (OR: 3.2, 95% CI: 1.2–8.6, and p 0.024), diabetes mellitus (OR: 2.9, 95% CI: 1.0–8.5,
andp 0.056), and oxygen saturation <92% (OR: 5.1, 95% CI: 1.8–14.4, and p 0.002). In this private health facility, mortality
was about 1 in 10 patients, and more people presented with critical illness in the second wave of the pandemic, and most deaths
occurred after 2 weeks of hospitalization.
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Citation
Apiyo, M., Olum, R., Kabuye, A., Khainza, B., Amate, A. M., Byabashaija, V., ... & Bongomin, F. (2022). Clinical characteristics and outcomes of patients hospitalized with COVID-19 at Case Hospital, Uganda. Interdisciplinary Perspectives on Infectious Diseases, 2022.