High Anion Gap Metabolic Acidosis among Children with Nodding Syndrome (NS) in Northern Uganda: Case Series
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Date
2013-11-25
Journal Title
Journal ISSN
Volume Title
Publisher
British Journal of Medicine & Medical Research
Abstract
Aims: To conduct a hormonal and biochemical studies on 10 patients with diagnosis of probable Nodding Syndrome (NS). Study Design: A cross-sectional study Place and Duration of Study: Atanga Health Center III in Pader District in Northern
Uganda in September 2012.
Methodology: We recruited consecutively 10 children with probable Nodding Syndrome who had been admitted for symptomatic management of seizures, injuries resulting from falls and nutritional rehabilitation. History, physical examinations, biophysical
measurements (anthropometry) and blood investigations including serum electrolytes, liver function tests, thyroid hormones and vitamin D assays. Ethical approval was obtained from Gulu University Institutional Review Committee.
Results: All children had severely low serum calcium and bicarbonate levels and a high Anion Gap. Thyroid hormones and vitamin D assays were largely normal.
Conclusion: Children with Nodding Syndrome undergoing treatment for seizure control and nutritional rehabilitation have high Anion Gap metabolic acidosis.
Description
Keywords
Nodding Syndrome, metabolic acidosis, high Anion Gap, hormones, Pader, Northern Uganda
Citation
Kitara, D. L., Mwaka, A. D., & Kigonya, E. (2014). High anion gap metabolic acidosis among children with Nodding Syndrome (NS) in Northern Uganda: case series. British Journal of Medicine and Medical Research, 4(6), 1301-1314.